4-Methylumbelliferyl N-acetyl-a-D-neuraminic acid ammonium
CAS:
Ref. 3D-EM09053
1mg
282.00€
2mg
414.00€
5mg
663.00€
Product Information
Name:4-Methylumbelliferyl N-acetyl-a-D-neuraminic acid ammonium
Brand:Biosynth
Description:4-Methylumbelliferyl N-acetyl-alpha-D-neuraminic acid ammonium is a fluorogenic substrate for neuraminidase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl N-acetyl-alpha-D-neuraminic acid ammoniumas a substrate for measuring the neuraminidase activity is used for detecting the glycoproteins on the surface of influenza A and B viruses, as well as for sialidosis diagnosis.
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Chemical properties
Molecular weight:471.44 g/mol
Formula:C21H28N2O11
Purity:Min. 95%
Color/Form:Powder
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