4-Methylumbelliferyl dodecanoate

CAS: 66185-71-5

Ref. 3D-EM168113

Product Information

• Name: 4-Methylumbelliferyl dodecanoate
• Brand: Biosynth
• Description: 4-Methylumbelliferyl dodecanoate is a fluorogenic substrate for lipase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl dodecanoateas a substrate for measuring the lipase activity is used for detecting pancreatic insufficiency in diagnosis assays as well as the screening of lipase deficiency.

Chemical properties

• Molecular weight: 358.47 g/mol
• Formula: C₂₂H₃₀O₄
• Purity: Min. 95%
• Color/Form: Powder