4-Methylumbelliferyl propionate

CAS: 3361-13-5

Ref. 3D-EM52254

Product Information

• Name: 4-Methylumbelliferyl propionate
• Synonyms: Propionic acid-4-methylumbelliferyl ester
• Brand: Biosynth
• Description: 4-Methylumbelliferyl propionate is a fluorogenic substrate for esterase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl propionateas a substrate for measuring the esterase activity is used for esterase deficiency screening assays.

Chemical properties

• Molecular weight: 232.23 g/mol
• Formula: C₁₃H₁₂O₄
• Purity: Min. 95 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C13H12O4/c1-3-12(14)16-9-4-5-10-8(2)6-13(15)17-11(10)7-9/h4-7H,3H2,1-2H3
• InChI key: InChIKey=IOKUIFTUULBXMB-UHFFFAOYSA-N
• SMILES: CCC(=O)Oc1ccc2c(C)cc(=O)oc2c1