4-Methylumbelliferyl lignocerate

CAS: 84434-52-6

Ref. 3D-EM65953

Product Information

• Name: 4-Methylumbelliferyl lignocerate
• Synonyms: 4-Methylumbelliferyl tetracosanate
• Brand: Biosynth
• Description: 4-Methylumbelliferyl lignocerate is a fluorogenic substrate for lipase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl lignocerateas a substrate for measuring the lipase activity is used for X-linked adrenoleukodystrophy diagnosis and peroxisomal disorder screening.

Chemical properties

• Molecular weight: 526.79 g/mol
• Formula: C₃₄H₅₄O₄
• Purity: Min. 95%
• Color/Form: Powder