Product Information
Name:BAY 12-17389
Synonyms:
- N-Cyclopropyl-4-[6-(2,3-difluoro-4-methoxyphenoxy)-8-[(3,3,3-trifluoropropyl)amino]imidazo[1,2-b]pyridazin-3-yl]-2-methylbenzamide
Brand:Biosynth
Description:BAY 12-17389 is a novel anticancer drug that inhibits the activity of CDK4 and CDK6. It is an imidazopyrazine derivative, which binds to the ATP-binding pocket of the enzyme, thereby preventing its activation. BAY 12-17389 has shown anticancer activity in animal models for skin cancer and bladder cancer. In vitro assays have demonstrated that BAY 12-17389 is effective at inhibiting proliferation of cultured cells from different types of human cancers. The effective dose for BAY 12-17389 is not yet known but it has been shown to be safe at doses as high as 2 µM.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:561.5 g/mol
Formula:C27H24F5N5O3
Purity:Min. 95%
Technical inquiry about: BAY 12-17389
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