2-O-(4-Nitrophenyl)-a-D-N-acetylneuraminic acid

CAS: 26112-88-9

Ref. 3D-EN29246

Product Information

• Name: 2-O-(4-Nitrophenyl)-a-D-N-acetylneuraminic acid
• Synonyms: PNP-a-NeuNAc, 2-O-(4-Nitrophenyl)-N-acetylneuraminic acid, 1-Npana, 4-Nitrophenyl-5-acetamido-3,5-dideoxy-alpha-D-glycero-D-galacto-2-nonulopyranosidonic acid, NP-Nan, p-Nitrophenyl N-acetyl-alpha-D-neuraminide, p-Nitrophenyl N-acetyl-alpha-neuraminide, D-glycero-alpha-D-galacto-2-Nonulopyranosidonic acid, 4-nitrophenyl 5-(acetylamino)-3,5-dideoxy-, (2S,4S,5R,6R)-5-(acetylamino)-4-hydroxy-2-(4-nitrophenoxy)-6-[(1R,2R)-1,2,3-trihydroxypropyl]tetrahydro-2H-pyran-2-carboxylate (non-preferred name), 4-nitrophenyl 5-(acetylamino)-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosidonato, 4-Nitrophenyl 5-(Acetylamino)-3,5-Dideoxynon-2-Ulopyranosidonic Acid

Description

2-O-(4-Nitrophenyl)-a-D-N-acetylneuraminic acid, also known as p-nitrophenyl N-acetylneuraminic acid, is a chromogenic substrate specifically designed for the detection and quantification of neuraminidase (sialidase) activity. Upon cleavage by neuraminidase, it releases a yellow-colored product, 4-nitrophenol, which can be easily monitored spectrophotometrically at 405 nm. This substrate is widely used in various applications, including enzyme kinetics studies, inhibitor screening, and the determination of neuraminidase activity in biological samples such as viruses, bacteria, and cell lysates. It is particularly useful for studying the enzymatic properties of neuraminidases from different sources and for the development of novel antiviral and antibacterial agents targeting neuraminidase activity.

• Brand: Biosynth

Chemical properties

• Molecular weight: 430.36 g/mol
• Formula: C₁₇H₂₂N₂O₁₁
• Purity: Min. 95 Area-%
• Color/Form: White Powder