ARS-853

CAS: 1629268-00-3

Ref. 3D-EQC26800

Product Information

• Name: ARS-853
• Brand: Biosynth
• Description: ARS-853 is a potent inhibitor of protein kinase C (PKC) and PKC-related enzymes. ARS-853 has been shown to be an activated, potent inhibitor of PKC in vivo in a mouse tumor model. The mechanism of inhibition is thought to be due to the binding of ARS-853 to the catalytic site of PKC, which blocks phosphatase activity. PKC inhibitors are used in cancer treatment because they help control cancer cell signaling pathways. ARS-853 has been shown to inhibit phosphatases, such as PTP1B, which regulate multiple cellular processes including glycogen synthesis, lipid metabolism, and insulin secretion.Pharmacokinetic studies have shown that ARS-853 is rapidly absorbed from the gastrointestinal tract and eliminated primarily by hepatic metabolism with a half-life of about 2 hours.

Chemical properties

• Molecular weight: 432.94 g/mol
• Formula: C₂₂H₂₉ClN₄O₃
• Purity: Min. 95%