Product Information
Name:AZ PFKFB3 26
Synonyms:
- (S)-N-(4-((3-Cyano-1-isobutyl-1H-indol-5-yl)oxy)phenyl)pyrrolidine-2-carboxamide
Brand:Biosynth
Description:AZ PFKFB3 26 is a mutant form of the protein PFKFB3, which is involved in the regulation of glycolysis and cell growth. This mutation causes the protein to become insensitive to inhibition by the drug AZD6244. The mutant form of PFKFB3 also has an aberrant metabolic phenotype that sensitizes cells to glucose deprivation and activates cell growth pathways such as glycolysis. These effects are caused by activating AMPK and mTORC1, two proteins that regulate cell metabolism.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:402.49 g/mol
Formula:C24H26N4O2
Purity:Min. 95%
Technical inquiry about: AZ PFKFB3 26
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