Product Information
GSK 9027 is a conjugate of the chemotherapeutic agent gemcitabine with an antisense oligodeoxynucleotide. The conjugate selectively targets prostate cancer cells and inhibits their growth without affecting normal cells. GSK 9027 has been shown to inhibit the expression of genes that are necessary for growth and proliferation, such as cyclin D1 and c-myc, in pancreatic cancer cells. It also has antitumor activity against infectious diseases, including cytomegalovirus infection in mice. GSK 9027 is currently being studied for use in inflammatory diseases, like rheumatoid arthritis, Crohn's disease, ulcerative colitis, psoriasis, and Alzheimer's disease.
Chemical properties
Technical inquiry about: 3D-EZB09688 GSK 9027
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