GS 9973

CAS: 1229208-44-9

Ref. 3D-EZB20844

Product Information

• Name: GS 9973
• Synonyms: 6-(1H-Indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine
• Brand: Biosynth
• Description: GS 9973 is a research drug that inhibits the activity of protein kinases, which are enzymes that regulate the function of other proteins. GS 9973 inhibits the activity of mcl-1, an effector protein in the apoptosis pathway and is currently being tested for its ability to inhibit cancer cells from spreading. GS 9973 has been shown to have a low risk of toxicity in humans and has been found to be safe for use in clinical trials with human pharmacokinetics. This drug also inhibits P-gp substrates, which prevents it from entering into the retina. The only side effects observed so far are eye disorders such as conjunctivitis and iritis.

Chemical properties

• Molecular weight: 411.47 g/mol
• Formula: C₂₃H₂₁N₇O
• Purity: Min. 95%