5-Aminoimidazole-4-carboxamide HCl

CAS: 21299-72-9

Ref. 3D-FA00577

Product Information

• Name: 5-Aminoimidazole-4-carboxamide HCl
• Synonyms: 1H-Imidazole-4-carboxamide, 5-amino-, 5-Amino-4-Imidazolylcarboxamide, 5-Amino-3H-Imidazole-4-Carboxamide, 5-Amino-4-Imidazolecarboxamide, 5-Aminoimidazole-4-Carboxamide, 4(5)-Amino-5(4)-Imidazolecarboxamide, 4-Amino-5-Imidazolecarboxamid, 5-Amino-1H-Imidazole-4-Carboxamid, 5-Amino-4-glyoxalinecarboxamide, 5-Amino-Imidazole-4-Carboxamid, Aic Aminoimidazolecarboxamide, Ba2756 Diazol-C, 1H-Imidazole-4-carboxamide, 5-amino- 5-amino-4-imidazolylcarboxamide, 4-Amino-5-imidazolecarboxamide monohydrate, AICA, 4-Amino-5-carbamoylimidazole, 4-Amino-5-imodazole, 4-Amino-5-imidazole carboxamide, 4-(1-Aminovinyl)-1H-imidazol-5-amine, Aica, 4-Amino-5-imidazolecarboxamide, 1H-imidazole-5-carboxamide, 4-amino-, 4-Amino-1H-imidazole-5-carboxamide, 5-Amino-1H-imidazole-4-carboxamide, 5-amino-Imidazole-4-carboxamide

Description

5-Aminoimidazole-4-carboxamide HCl (5-AICA) is a compound that is used for the treatment of bowel disease. It inhibits the synthesis of 5'-nucleotidase and phosphoribosyl transferase, which are enzymes responsible for the conversion of nucleotide monophosphates to nucleotide diphosphates. This inhibition leads to a decrease in the amount of adenosine triphosphate (ATP) produced by cells, which may be due to its ability to inhibit ATP synthase activity. 5-AICA also has been shown to bind to DNA and inhibit transcriptional activities. The binding of 5-AICA may be due to its ability to form hydrogen bonds with guanine residues in DNA or its capability to form covalent bonds with thymidine residues in DNA. 5-AICA also has been shown to have cytotoxic effects on HL60 cells, as well as other

• Brand: Biosynth

Chemical properties

• Molecular weight: 126.12 g/mol
• Purity: Min. 95%
• Color/Form: Powder