5-Aminoimidazole-4-carboxamide HCl

CAS: 21299-72-9

Ref. 3D-FA00577

Product Information

• Name: 5-Aminoimidazole-4-carboxamide HCl
• Brand: Biosynth
• Description: 5-Aminoimidazole-4-carboxamide HCl (5-AICA) is a compound that is used for the treatment of bowel disease. It inhibits the synthesis of 5'-nucleotidase and phosphoribosyl transferase, which are enzymes responsible for the conversion of nucleotide monophosphates to nucleotide diphosphates. This inhibition leads to a decrease in the amount of adenosine triphosphate (ATP) produced by cells, which may be due to its ability to inhibit ATP synthase activity. 5-AICA also has been shown to bind to DNA and inhibit transcriptional activities. The binding of 5-AICA may be due to its ability to form hydrogen bonds with guanine residues in DNA or its capability to form covalent bonds with thymidine residues in DNA. 5-AICA also has been shown to have cytotoxic effects on HL60 cells, as well as other

Chemical properties

• Molecular weight: 126.12 g/mol
• Purity: Min. 95%
• Color/Form: Powder