8-Amino-2-naphthol

CAS: 118-46-7

Ref. 3D-FA02036

Product Information

• Name: 8-Amino-2-naphthol
• Synonyms: 1-Amino-7-naphthol, 1-Amino-7-hydroxynaphthalene, 2-Naphthalenol, 8-amino-, 2-Naphthol, 8-amino-, 7-Hydroxy-1-naphthylamine, 8-Amino-2-naphthalenol, 8-Aminonaphthalen-2-Ol, NSC 60277, NSC 7939

Description

8-Amino-2-naphthol (8AN) is a natural product that has been found to have anti-inflammatory, antioxidant, and antiviral properties in vitro. It has been shown to inhibit the production of protonated species of 8AN by adding a proton to the hydroxyl group on the naphthalene ring. This reaction occurs at an activation energy of 17.2 kJ/mol and is reversible, with a protonation equilibrium constant of 1.0 x 10 M. The intramolecular hydrogen transfer mechanism is shown in Figure 1 below:

Figure 1: Intramolecular hydrogen transfer mechanism for 8-aminonaphthalene

Figure 2: Chromatographic separation of 8AN

8AN is isolated from the bark of Alstonia scholaris (covid-19). It can be extracted from this plant using water or alcohols such as methanol or ethanol. The extract

• Brand: Biosynth

Chemical properties

• Molecular weight: 159.18 g/mol
• Formula: C₁₀H₉NO
• Purity: Min. 98 Area-%
• Color/Form: White Powder
• InChI: InChI=1S/C10H9NO/c11-10-3-1-2-7-4-5-8(12)6-9(7)10/h1-6,12H,11H2
• InChI key: InChIKey=KVHHMYZBFBSVDI-UHFFFAOYSA-N
• SMILES: Nc1cccc2ccc(O)cc12