8-Azahypoxanthine

CAS: 2683-90-1

Ref. 3D-FA03012

Product Information

• Name: 8-Azahypoxanthine
• Synonyms: 1H,4H,7H-[1,2,3]Triazolo[4,5-d]pyrimidin-7-one, 1H-1,2,3-Triazolo[4,5-d]pyrimidin-7-ol, 1H-v-Triazolo[4,5-d]pyrimidin-7-ol, 2,3-Dihydrotriazolo[4,5-d]pyrimidin-7-one, 2,3-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one, 3,6-Dihydro-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one, 3,7a-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one, 4,5-dihydro-1H-triazolo(4,5-d)pyrimidin-4-ol, 7-Hydroxy-1,2,3,4,6-pentaazaindene, 7-Hydroxy-v-triazolo[d]pyrimidine, 7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one, 1,4-dihydro-, 7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one, 3,6-dihydro-, 7H-v-Triazolo[4,5-d]pyrimidin-7-one, 1,6-dihydro-, NSC 22709

Description

8-Azahypoxanthine is a hydroxyl analog of hypoxanthine. It contains a nitrogen atom in place of the oxygen atom on the 2-position. 8-Azahypoxanthine has been shown to be an effective inhibitor of purine biosynthesis in yeast cells and can be used as a replacement for xanthine during the synthesis of adenosine triphosphate (ATP) from uracil. 8-Azahypoxanthine was found to have good detection sensitivity, with an estimated detection limit of 0.2 µM. The optimum pH for this compound is 7.8, which is similar to that of wild type strain and tissue culture media. Mutants resistant to 8-azahypoxanthine were generated by exposure to high concentrations (>100 mM) for long periods (>2 days). Mutant strains showed no detectable enzyme activity against orotic acid or glycosidic bond formation with erythromycin

• Brand: Biosynth

Chemical properties

• Molecular weight: 137.1 g/mol
• Purity: Min. 95%
• Color/Form: Powder