3-Aminoquinuclidine dihydrochloride

CAS: 6530-09-2

Ref. 3D-FA03742

Product Information

• Name: 3-Aminoquinuclidine dihydrochloride
• Brand: Biosynth
• Description: 3-Aminoquinuclidine dihydrochloride (3-AQDH) is a chiral quinuclidine derivative that is an acetylcholine receptor agonist. It has been shown to bind to the α7 nicotinic acetylcholine receptor with high affinity and selectivity. 3-AQDH has also been shown to crosslink the cholinergic receptor, which may lead to increased sensitivity of the receptor. The binding constants between 3-AQDH and the α7 nicotinic acetylcholine receptors are very high and it has been shown to be enantiopure in its synthesis. 3-AQDH also has a hydrophilic interaction chromatography profile, which separates it from other compounds. This agent may have potential use as a drug for treating Alzheimer's disease and Parkinson's disease due to its ability to inhibit acetylcholinesterase activity.

Chemical properties

• Molecular weight: 199.12 g/mol
• Purity: Min. 95%
• Color/Form: Powder