2-Amino-6-hydroxy-8-mercaptopurine

CAS: 6324-72-7

Ref. 3D-FA09809

Product Information

• Name: 2-Amino-6-hydroxy-8-mercaptopurine
• Synonyms: 2-Amino-1,7,8,9-tetrahydro-8-thioxo-6H-purin-6-one, 2-Amino-8-mercapto-7H-purin-6-ol, 2-Amino-8-sulfanyl-6,7-dihydro-1H-purin-6-one, 2-Amino-8-sulfanyl-6,9-dihydro-1H-purin-6-one, 2-Amino-8-sulfanyl-9H-purin-6-ol, 2-Amino-8-sulfanylidene-7,9-dihydro-3H-purin-6-one, 2-Amino-8-thioxo-1,7,8,9-tetrahydro-purin-6-one, 2-Amino-8-thioxo-3,7,8,9-tetrahydro-6H-purin-6-one, 2-amino-1,7,8,9-tetrahydro-2-thioxo-6H-purin-6-one, 2-amino-8-mercapto-9H-purin-6-ol, 2-amino-8-sulfanyl-7H-purin-6-ol, 228-686-9, 6H-Purin-6-one, 2-amino-1,7,8,9-tetrahydro-8-thioxo-, 6H-purin-6-one, 2-amino-3,7,8,9-tetrahydro-8-thioxo-, 7H-purin-6-ol, 2-amino-8-mercapto-, 8-Mercaptoguanine, 8-Thioguanine, 9H-purin-6-ol, 2-amino-8-mercapto-, Guanine, 8-mercapto-, NSC 29188

Description

2-Amino-6-hydroxy-8-mercaptopurine is an antimicrobial agent that inhibits the growth of bacteria by binding to their ribosomes. It has been shown to have a cytotoxic effect in vivo on cancer cells and intestinal parasites, as well as a protective effect against infectious diseases. 2-Amino-6-hydroxy-8-mercaptopurine has also been shown to inhibit the synthesis of proteins in vitro, which may be due to its ability to bind to the ribosomal subunit and inhibit protein synthesis. 2-Amino-6-hydroxy-8-mercaptopurine inhibits bacterial growth by binding to DNA dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or gluc

• Brand: Biosynth

Chemical properties

• Molecular weight: 183.19 g/mol
• Formula: C₅H₅N₅OS
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C5H5N5OS/c6-4-8-2-1(3(11)10-4)7-5(12)9-2/h(H5,6,7,8,9,10,11,12)
• InChI key: InChIKey=JHEKNTQSGTVPAO-UHFFFAOYSA-N
• SMILES: Nc1nc2[nH]c(=S)[nH]c2c(=O)[nH]1