Product Information
- Alamifovir [INN]
- Bis(2,2,2-trifluoroethyl) ((2-(2-amino-6-((4-methoxyphenyl)sulfanyl)-9H-purin-9-yl)ethoxy)methyl)phosphonate
- Ly 582563
- Ly582563
- Mcc 478
- Unii-0N739K2A8A
- Phosphonic acid, ((2-(2-amino-6-((4-methoxyphenyl)thio)-9H-purin-9-yl)ethoxy)methyl)-, bis(2,2,2-trifluoroethyl) ester
- bis(2,2,2-trifluoroethyl) ({2-[2-amino-6-(phenylsulfanyl)-9H-purin-9-yl]ethoxy}methyl)phosphonate
Alamifovir is a drug that inhibits the replication of viruses by blocking the activity of a viral enzyme called NS3 protease. It is used in the treatment of chronic viral hepatitis, including hepatitis C and HIV-AIDS. Alamifovir has been shown to inhibit the growth of virus resistant mutants with nitro groups, which are not inhibited by other drugs. This drug has also been shown to be effective in preventing liver lesions caused by lamivudine-resistant hepatitis. Alamifovir is an acyclic nucleoside phosphonate that contains a phenolic acid group and is active against both wild-type and lamivudine-resistant strains of hepatitis C virus (HCV).
Chemical properties
Technical inquiry about: 3D-FA104025 Alamifovir
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