Amyloid β-Protein (10-20)

CAS: 152286-31-2

Ref. 3D-FA108433

Product Information

• Name: Amyloid β-Protein (10-20)
• Synonyms: ?-Amyloid (10-20)H-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-OH
• Brand: Biosynth
• Description: Amyloid beta-protein (Aβ) is a peptide that is found in the brain. Aβ has been shown to be involved in Alzheimer's disease, Parkinson's disease, and other neurodegenerative diseases. Aβ can be used as a biomarker for these diseases because it accumulates in the brain and blood of patients with these diseases. It is hypothesized that Aβ binds to cell surface proteins, such as choline receptors, which disrupts the function of neurons. This leads to decreased production of acetylcholine and eventual death of neurons. This study sought to identify inhibitors of Aβ aggregation by screening a library of small molecules against Aβ aggregates. The screen identified several potential anticancer compounds that are acidic and reactive. These compounds have been shown to inhibit polymerase chain reaction (PCR) amplification at nanomolar concentrations. In addition, they have been shown to reduce the expression of phosphofructokinase (PFK), an enzyme important in gly

Chemical properties

• Molecular weight: 1,446.65 g/mol
• Formula: C₇₁H₉₉N₁₇O₁₆
• Purity: Min. 95%