Product Information
Name:AF-2
Synonyms:
- H-Lys-His-Glu-Tyr-Leu-Arg-Phe-NH2 H-KHEYLRF-NH2
Brand:Biosynth
Description:AF-2 is a potent, selective and competitive antagonist at the nicotinic acetylcholine receptor (nAChR). AF-2 binds to the extracellular domains of the nAChR and prevents agonists from binding. It has been shown to inhibit acetylcholine release in isolated heart preparations with high affinity and selectivity. The drug has been tested as an anthelmintic against Caenorhabditis elegans and found to be effective. AF-2 is a cholinergic compound that binds to ganglia, leading to a biphasic response. It also has significant effects on the central nervous system, inhibiting both nicotinic and muscarinic acetylcholine receptors.AF-2 is sequenced according to the following formula: H-Lys-His-Glu-Tyr-Leu-Arg-Phe NH2
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:991.15 g/mol
Formula:C47H70N14O10
Purity:Min. 95%
Technical inquiry about: AF-2
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