Atrial Natriuretic Factor (4-28) (human, bovine, porcine)

CAS: 95896-08-5

Ref. 3D-FA108575

Product Information

• Name: Atrial Natriuretic Factor (4-28) (human, bovine, porcine)
• Synonyms: hANF (4-28), Anaritide, Atrial Natriuretic Polypeptide (4-28), humanH-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-S er-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH (Disulfide bond)
• Brand: Biosynth
• Description: Atrial natriuretic factor (ANF) is a hormone that plays an important role in the regulation of sodium excretion and blood pressure. It binds to two different receptor sites, which are located on the cell membrane. The ANF-A receptor is found in the atria of the heart and the ANF-B receptor is found in the kidneys. ANF has been shown to increase water excretion from the kidneys and decrease blood pressure by increasing sodium excretion from the kidneys and decreasing salt retention. Atrial natriuretic factor (4-28) is a disulfide form of ANF that has a high affinity for its receptors. This agent can be labeled with a radioactive atom for use as an experimental tool for determining binding sites. Atrial natriuretic factor (4-28) can also be chemically conjugated with polymers, such as polyethylene glycol, to make it more water soluble and therefore more useful as a drug candidate.

Chemical properties

• Molecular weight: 2,724.03 g/mol
• Formula: C₁₁₂H₁₇₅N₃₉O₃₅S₃
• Purity: Min. 95%
• Color/Form: Solid