Atriopeptin III (rat)

CAS: 90817-13-3

Ref. 3D-FA108606

Product Information

• Name: Atriopeptin III (rat)
• Synonyms: H-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH H-SSCFGGRIDRIGAQSGLGCNSFRY-OH, H-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH (Disulfide bond), Atriopeptin III, Rat

Description

Atriopeptin III is a peptide hormone that belongs to the atrial natriuretic peptide group. It is an analog of atrial natriuretic peptide (ANP), which regulates blood pressure and sodium excretion, and has minimal toxicity. The disulfide bond between Cys-Cys and Cys-Gly on the N terminus of Atriopeptin III is necessary for its activity. The enzyme responsible for this disulfide bond formation is thioredoxin reductase, which is found in the cytoplasm of cells. Atriopeptin III has been shown to inhibit cyclase activity in renal proximal tubular cells, as well as congestive heart failure in rats. It also inhibits fatty acid synthesis by inhibiting carnitine acyltransferase I, leading to increased levels of free fatty acids and diacylglycerols in the blood plasma.

• Brand: Biosynth

Chemical properties

• Molecular weight: 2,549.8 g/mol
• Formula: C₁₀₇H₁₆₅N₃₅O₃₄S₂
• Purity: Min. 95%