(D-Ala2,D-Leu5)-Enkephalin

CAS: 63631-40-3

Ref. 3D-FA108791

Product Information

• Name: (D-Ala2,D-Leu5)-Enkephalin
• Synonyms: H-Tyr-D-Ala-Gly-Phe-D-Leu-OH H-Y(dA)GF(dL)-OH, D-Leucine ,N-[N-[N-(N-L-tyrosyl-D-alanyl)glycyl]-L-phenylalanyl]-, (2-D-Ala,5-D-Leu)-enkephalin, 161: PN: US20030176421 PAGE: 54-55 claimedprotein, 2-D-Alanine-5-D-leucine-enkephalin, Bw 180, Bw 180C, Dadl, Dadle, Tyr-D-Ala-Gly-Phe-D-Leu, Tyr-D-Ala-Gly-Phe-D-Leu-OH, Tyrosyl-D-alanylglycylphenylalanyl-D-leucine, [D-Ala2-D-Leu5]enkephalin, [D-Alanine2-Leucine5]enkephalin, H-Tyr-D-Ala-Gly-Phe-D-Leu-OH

Description

Enkephalin is a peptide belonging to the group of opioid drugs. It is a neurotransmitter that binds to kappa-opioid receptors and μ-opioid receptors. Enkephalin has been shown to inhibit voltage-dependent calcium channels and mitochondrial membrane potential in neurons, which leads to neuronal death. This drug also inhibits the production of cyclic guanine monophosphate (cGMP) by inhibiting guanine nucleotide-binding proteins at the plasma membrane, leading to a decrease in the synthesis of proteins and DNA. The dextran sulfate test can be used to measure enkephalin activity by precipitating it from solution with sodium sulfate. Additionally, this drug can be used as a p-gp inhibitor for the treatment of cancer cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 569.65 g/mol
• Formula: C₂₉H₃₉N₅O₇
• Purity: Min. 95%