Acetyl-(Pro18,Asp21)-Amyloid b-Protein (17-21) amide
CAS: 339990-02-2
Ref. 3D-FA109732
| 10mg | 181.00 € | ||
| 25mg | 339.00 € | ||
| 50mg | 511.00 € | ||
| 100mg | 835.00 € | ||
| 250mg | 1,703.00 € |
Product Information
- iA?5p
- Beta-sheet Breaker Peptide ?iA 5pAc-Leu-Pro-Phe-Phe-Asp-NH2
- 10:PN: WO03050139 SEQID: 15 claimed protein
- 3: PN: WO0134631 PAGE: 35 claimedprotein
- As 602704
- Ac-Leu-Pro-Phe-Phe-Asp-Nh2
Acetyl-(Pro18,Asp21)-Amyloid b-Protein (17-21) amide is a peptide that was generated by incubating β-amyloid with the protease papain. This peptide has been shown to induce population and biochemical changes in cells, including focusing of β-amyloid aggregates. It also induces reactive oxygen species and promotes extracellular protofibril formation. Acetyl-(Pro18,Asp21)-Amyloid b-Protein (17-21) amide is a conjugate of acetylated lysine residues and amyloid β-protein that can be used as an anti-amyloid therapeutic. The peptide is characterized by dichroism spectroscopy, which has revealed its specific binding to the fibrils' surface.
Chemical properties
Technical inquiry about: 3D-FA109732 Acetyl-(Pro18,Asp21)-Amyloid b-Protein (17-21) amide
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