3-Acetylindole

CAS: 703-80-0

Ref. 3D-FA10988

Product Information

• Name: 3-Acetylindole
• Synonyms: 1-(1H-Indol-3-yl)ethanone3-Indolyl methyl ketone, 1-(1H-Indol-3-yl)ethan-1-one, 1-(1H-indol-3-yl)ethanone, 3-Acetyl-1H-indole, 3-Indolyl methyl ketone, Ethanone, 1-(1H-indol-3-yl)-, Iflab-Bb F1727-0313, Ketone, indol-3-yl methyl, NSC 47180, NSC 58084, Timtec-Bb Sbb003977

Description

3-Acetylindole is a dibenzopyran compound that has been shown to have anti-inflammatory properties. 3-Acetylindole inhibits the acylation reaction of arachidonic acid with coenzyme A and thereby blocks the production of prostaglandin E2. This compound also binds to the benzene ring, which may be due to its acidic nature. 3-Acetylindole has been shown to inhibit T-cell leukemia and other cancers in animal models. It has also been shown to inhibit the growth of cancer cells in culture by blocking DNA synthesis and inhibiting proliferation. The binding constants for this compound have been determined by x-ray crystal structures and protonation studies.

• Brand: Biosynth

Chemical properties

• Molecular weight: 159.18 g/mol
• Formula: C₁₀H₉NO
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C10H9NO/c1-7(12)9-6-11-10-5-3-2-4-8(9)10/h2-6,11H,1H3
• InChI key: InChIKey=VUIMBZIZZFSQEE-UHFFFAOYSA-N
• SMILES: CC(=O)c1c[nH]c2ccccc12