H-Asp-Asp-Asp-OH

CAS: 107208-63-9

Ref. 3D-FA110342

Product Information

• Name: H-Asp-Asp-Asp-OH
• Brand: Biosynth
• Description: H-Asp-Asp-Asp-OH is a peptide that has been shown to disrupt the cytosol and cause apoptosis. It can also induce proteolytic maturation and modulate autocatalytic functions. H-Asp-Asp-Asp-OH induces apoptosis by activating caspase 9 and caspase 3, which cleaves poly (ADP ribose) polymerase (PARP). This leads to DNA fragmentation, chromatin condensation, nuclear fragmentation, cell shrinkage, membrane blebbing, and nuclear pyknosis. H-Asp-Asp-Asp-OH binds to the regulatory domain of caspase 9 and prevents it from being activated. The peptide also activates caspase 8 by binding to its regulatory domain, which then activates caspases 3 and 7. H-Asp-Asp-Asp-OH also stimulates the release of granzyme B from cytot

Chemical properties

• Molecular weight: 363.28 g/mol
• Formula: C₁₂H₁₇N₃O₁₀
• Purity: Min. 95%