Product Information
- AnthopleurinA
- Neurotoxin AX-I
- H-Gly-Val-Ser-Cys-Leu-Cys-Asp-Ser-Asp-Gly-Pro-Ser-Val-Arg-Gly-Asn-Thr-Leu-Ser-Gly-Thr-Leu-Trp-Leu-Tyr-Pro-Ser-Gly-Cys-Pro-Ser-Gly-Trp-His-Asn-Cys-Lys-Ala-His-Gly-Pro-Thr-Ile-Gly-Trp-Cys-Cys-Lys-Gln-OH (Disulfide bonds between Cys4 and Cys46/Cys6 and Cys3
Anthopleurin-A is a molecule that belongs to the group of cyclic peptides. It is a disulfide bond-containing molecule, which has been shown to inhibit the uptake of Na+ ions in cardiac tissue by binding to the Na+ channel. This leads to an increase in the intracellular concentration of Na+, which triggers a series of reactions leading to cell depolarization and stimulation of heart muscle contraction. Anthopleurin-A has also been shown to have stem cell factor-like activity in experimental models, which may be due to its ability to stimulate proliferation of stem cells.
Chemical properties
Technical inquiry about: 3D-FA110442 Anthopleurin-A
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