Ac-Ser-Gln-Asn-Tyr-OH

CAS: 129521-68-2

Ref. 3D-FA110462

Product Information

• Name: Ac-Ser-Gln-Asn-Tyr-OH
• Synonyms: Ac-SQNY
• Brand: Biosynth
• Description: Ac-Ser-Gln-Asn-Tyr-OH is an oligopeptide that is a substrate for enzymes that catalyze the hydrolysis of peptides. Ac-Ser-Gln-Asn-Tyr-OH has been shown to be an effective inhibitor of elastase and other proteases, with a kinetic mechanism involving a serine residue at position 1 as the nucleophile. This inhibitor binds to the active site of elastase and prevents access by the substrate. Acetylation at the C terminus may increase solubility, while substitution of tyrosine with a phenylalanine or tryptophan residue increases inhibitory activity. The optimum pH for this enzyme is around 7, while it’s inorganic nature makes it less sensitive to organic solvents.

Chemical properties

• Molecular weight: 552.53 g/mol
• Formula: C₂₃H₃₂N₆O₁₀
• Purity: Min. 95%