Product Information
Name:Ac-Ala-Pro-Ala-pNA
Brand:Biosynth
Description:Ac-Ala-Pro-Ala-pNA is a transition-state analog inhibitor of serine proteases. In the catalytic cleft, Ac-Ala-Pro-Ala-pNA mimics the carbonyl group and minimizes the active site serine. The hydroxyl group in this compound is responsible for its transition state buildup that leads to hydrolytic reactions. Acetal formation can be observed as an intermediate step in this reaction. Acetal formation occurs when a hydroxylic oxygen atom reacts with a terminal alkoxy or thiohydroxylic carbon atom on the reactant molecule. This reaction is catalyzed by enzymes such as alcohol dehydrogenase, acetaldehyde dehydrogenase, and acetyl transferase.
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Chemical properties
Molecular weight:419.43 g/mol
Formula:C19H25N5O6
Purity:Min. 95%
Technical inquiry about: Ac-Ala-Pro-Ala-pNA
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