Ac-DL-Phe-pNA
CAS: 19746-42-0
Ref. 3D-FA110699
| 2g | 232.00 € | ||
| 5g | 434.00 € | ||
| 10g | 658.00 € | ||
| 25g | 1,178.00 € | ||
| 50g | 2,050.00 € |
Product Information
- 2-Acetamido-N-(4-nitrophenyl)-3-phenylpropanamide
- 2-Acetylamino-N-(4-nitro-phenyl)-3-phenyl-propionamide
- Benzenepropanamide, α-(acetylamino)-N-(4-nitrophenyl)-
- Hydrocinnamanilide, α-acetamido-4′-nitro-, <span class="text-smallcaps">DL</span>-
- α-(Acetylamino)-N-(4-nitrophenyl)benzenepropanamide
Ac-DL-Phe-pNA is a synthetic derivative of the natural substrate Ac-Lys-pNA. It binds to the active site of serine proteases and blocks the release of their active form, which results in inhibition of collagen synthesis. The reaction is reversible and it can be hydrolyzed by chymotrypsin or elastase. Ac-DL-Phe-pNA has been shown to inhibit protein-protein interactions between epimastigotes and extracellular matrix proteins, leading to cell death. This compound has also been found to have an optimum pH of 6.5, which is neutral.
Chemical properties
Technical inquiry about: 3D-FA110699 Ac-DL-Phe-pNA
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