Ac-Ile-Glu-Pro-Asp-pNA

CAS: 216757-29-8

Ref. 3D-FA110813

Product Information

• Name: Ac-Ile-Glu-Pro-Asp-pNA
• Synonyms: Ac-IEPD-pNA
• Brand: Biosynth
• Description: Ac-Ile-Glu-Pro-Asp-pNA is a synthetic peptide that has been shown to induce apoptosis in tumor cells. The peptide was found to cause cell lysis and necrotic cell death, which is associated with the activation of serine proteases. Ac-Ile-Glu-Pro-Asp-pNA also has been shown to have a toxicity profile similar to other apoptotic agents such as staurosporine, but it has not been tested for its ability to kill cancer cells without causing damage to healthy cells. Ac-Ile-Glu-Pro-Asp-pNA induces mitochondrial membrane depolarization and protein synthesis inhibition in K562 cells, which are human erythroleukemia cells. This peptide also has shown an ability to bind with monoclonal antibodies and inhibit the growth of casein.

Chemical properties

• Molecular weight: 634.64 g/mol
• Formula: C₂₈H₃₈N₆O₁₁
• Purity: Min. 95%