3-Acetyl-4-hydroxy-2H-chromen-2-one
CAS: 2555-37-5
Ref. 3D-FA121787
1g | 454.00 € | ||
2g | 669.00 € | ||
5g | 1,125.00 € | ||
250mg | 272.00 € | ||
500mg | 410.00 € |
Product Information
- 2H-1-benzopyran-2-one
- 3-acetyl-4-hydroxy-
- 2H-1-Benzopyran-2-one, 3-acetyl-4-hydroxy-
- 3-Acetyl-4-hydroxy-2H-1-benzopyran-2-one
- 3-Acetyl-4-hydroxychromen-2-one
- 3-Acetyl-4-hydroxycoumarin
- 3-acetyl-2-hydroxy-4H-chromen-4-one
- 3-acetyl-4-hydroxy-2H-chromen-2-one
- 4-Hydroxy-3-acetylcoumarin
- Coumarin, 3-acetyl-4-hydroxy-
- See more synonyms
- Nsc 11840
3-Acetyl-4-hydroxy-2H-chromen-2-one is a potent inhibitor of human lipoxygenase and soybean lipoxygenase. This compound has been shown to inhibit the growth of cancer cells in culture, with IC50 values ranging from 1.5 to 8.0 μM. 3-Acetyl-4-hydroxy-2H-chromen-2-one inhibits the activation of hydrogen peroxide by inhibiting the activity of enzymes such as amine oxidases and coumarin hydroxylases that are involved in the production of hydrogen peroxide. 3-(3'-acetylphenyl)acrylic acid (3APAA), which is structurally related to 3-(3'-acetylphenethyl)acrylic acid, was identified as an additional metabolite for this compound. The molecular docking analysis of these two compounds revealed that they have similar binding modes with regard to their binding affinity for the enzyme active
Chemical properties
Technical inquiry about: 3D-FA121787 3-Acetyl-4-hydroxy-2H-chromen-2-one
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