3-Aminocoumarin

Ref. 3D-FA13065

Product Information

• Name: 3-Aminocoumarin
• Synonyms: 3-Amino-2H-chromen-2-one3-Coumarinamin3-Amino-2-benzopyrone
• Brand: Biosynth
• Description: 3-Aminocoumarin is a coumarin derivative that inhibits the activity of dipeptidyl peptidase IV (DPP-IV), an enzyme that degrades the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). 3-Aminocoumarin has been shown to inhibit tumor growth and induce apoptosis in cancer cells. It also binds to copper, which may be related to its anticancer activity. 3-Aminocoumarin is a chiral compound that can exist as either of two enantiomers: L and D. The L form is considered more potent than the D form.; 3-Aminocoumarin can be synthesized by reacting malic acid with a phenylacetic acid derivative in the presence of ammonia or ammonium hydroxide.

Chemical properties

• Molecular weight: 161.16 g/mol
• Formula: C₉H₇NO₂
• Purity: Min. 95%
• Color/Form: Solid
• InChI: InChI=1S/C9H7NO2/c10-7-5-6-3-1-2-4-8(6)12-9(7)11/h1-5H,10H2
• InChI key: InChIKey=QWZHDKGQKYEBKK-UHFFFAOYSA-N
• SMILES: Nc1cc2ccccc2oc1=O