Acridine-3,6-diamine

CAS: 92-62-6

Ref. 3D-FA132623

Product Information

• Name: Acridine-3,6-diamine
• Synonyms: 3,6-acridinediamine, 3,6-Acridinediamine, 3,6-Diaminoacridine, 3,7-Diamino-5-azaanthracene, Acridine, 3,6-diamino-, Acridine-1,7-Diamine, Acridine-3,6-Diamine, Acriflavin A, Isoflav base, Proflavin, Proflavina

Description

Acridine-3,6-diamine is a fluorescent dye that is used in analytical chemistry to measure the concentration of DNA. The dye binds to the enzyme form of DNA and can be detected with a fluorescence microscope. Acridine-3,6-diamine is also used as a model system for studying multidrug efflux pumps found in cells, which are ATPases that pump out toxic substances from bacteria. This drug has shown antibacterial efficacy against various bacteria, including Staphylococcus aureus and Escherichia coli. The potential mechanism of action may be due to inhibition of the bacterial DNA replication processes by binding to the cell nuclei or through inhibition of energy metabolism or dinucleotide phosphate synthesis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 209.25 g/mol
• Formula: C₁₃H₁₁N₃
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C13H11N3/c14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10/h1-7H,14-15H2
• InChI key: InChIKey=WDVSHHCDHLJJJR-UHFFFAOYSA-N
• SMILES: Nc1ccc2cc3ccc(N)cc3nc2c1