5-Carboxycytosine

CAS: 3650-93-9

Ref. 3D-FA137002

Product Information

• Name: 5-Carboxycytosine
• Synonyms: 4-Amino-2-hydroxy-5-pyrimidinecarboxylic acid, 5-Carboxylcytosine, 5-Pyrimidinecarboxylic acid, 4-amino-1,2-dihydro-2-oxo-, 5-Pyrimidinecarboxylic acid, 6-amino-1,2-dihydro-2-oxo-, 6-Amino-1,2-dihydro-2-oxo-5-pyrimidinecarboxylic acid, 6-Amino-2-Oxo-1,2-Dihydropyrimidine-5-Carboxylic Acid, NSC 9309

Description

5-Carboxycytosine is a glycosylase that catalyses the removal of a sugar molecule from 5-carboxymethylaminomethyluracil (5-CMAM) to form 5-carboxymethylaminomethyluracil (5-CMA), which is not found in mammalian cells. The enzyme is a member of the family of glycosylases, which use hydrogen bonds to cleave the carbon-oxygen bond. It has been shown to be involved in transcriptional regulation and DNA repair. 5-Carboxycytosine has also been used as an analytical reagent for determining the presence of 5-CMAM in DNA samples.
5-Carboxycytosine has been shown to induce cellular transformation, which may be due to its ability to bind dna with high affinity and act as a template for dna synthesis. It is also able to produce 5-C

• Brand: Biosynth

Chemical properties

• Molecular weight: 155.11 g/mol
• Formula: C₅H₅N₃O₃
• Purity: Min. 95%
• Color/Form: Powder