Arotinolol hydrochloride

CAS: 68377-91-3

Ref. 3D-FA146940

Product Information

• Name: Arotinolol hydrochloride
• Brand: Biosynth
• Description: Arotinolol hydrochloride is a beta-blocker that, in contrast to propranolol, has a higher selectivity for the β1 receptor. It is used to treat hypertension and angina pectoris. Arotinolol hydrochloride lowers blood pressure by inhibiting the activity of α-adrenergic receptors, which are found in the heart and vascular smooth muscle. This inhibition reduces the release of norepinephrine and causes vasodilation. Arotinolol hydrochloride also has a positive effect on cardiac function as it decreases myocardial oxygen demand and increases coronary flow. Arotinolol hydrochloride has been shown to lower systolic pressure in anesthetized dogs with an intravenous dose of sodium citrate. The drug also lowers diastolic pressure in conscious dogs at doses of 0.5 mg/kg (0.2 mg/lb) or greater when given intravenously or subcutaneously.

Chemical properties

• Molecular weight: 408 g/mol
• Formula: C₁₅H₂₂ClN₃O₂S₃
• Purity: Min. 98%
• Color/Form: Powder