2-Azabicyclo[3.3.0]octane-3-carboxylicacid

CAS: 109428-53-7

Ref. 3D-FA150108

Product Information

• Name: 2-Azabicyclo[3.3.0]octane-3-carboxylicacid
• Synonyms: Cyclopenta[b]pyrrole-2-carboxylic acid, octahydro-, (2S,3aS,6aS)- (9CI), (2S,3aS,6aS)-octahydrocyclopenta[b]pyrrole-2-carboxylic acid, Octahydrocyclopenta[B]Pyrrole-2-Carboxylic Acid

Description

2-Azabicyclo[3.3.0]octane-3-carboxylicacid (2ABA) is a potent aminopeptidase inhibitor that has been shown to be effective in the treatment of central nervous system diseases such as epilepsy and Alzheimer's disease. 2ABA is an enzyme inhibitor that binds to the active site of aminopeptidases, preventing the hydrolysis of peptides. This inhibition leads to increased levels of peptides in the brain, which may lead to an increase in the production of neurotransmitters, resulting in therapeutic effects for central nervous system diseases. 2ABA has also been shown to potentiate angiotensin II, which may be due to its ability to inhibit angiotensin converting enzyme (ACE). ACE inhibitors are used for hypertension and congestive heart failure because they decrease blood pressure by increasing vasodilation and reducing peripheral vascular resistance. The 2ABA also inhibits octapeptide

• Brand: Biosynth

Chemical properties

• Molecular weight: 155.19 g/mol
• Formula: C₈H₁₃NO₂
• Purity: Min. 95%
• InChI: InChI=1S/C8H13NO2/c10-8(11)7-4-5-2-1-3-6(5)9-7/h5-7,9H,1-4H2,(H,10,11)/t5-,6-,7-/m0/s1
• InChI key: InChIKey=OQHKEWIEKYQINX-ACZMJKKPSA-N
• SMILES: O=C(O)[C@@H]1C[C@@H]2CCC[C@@H]2N1