2-Amino-3-(4-hydroxy-3-methoxyphenyl)propanoic acid

CAS: 7636-26-2

Ref. 3D-FA153636

Product Information

• Name: 2-Amino-3-(4-hydroxy-3-methoxyphenyl)propanoic acid
• Brand: Biosynth
• Description: 2-Amino-3-(4-hydroxy-3-methoxyphenyl)propanoic acid is a metabolite of levodopa in the body. It is formed by oxidation of levodopa via the enzyme catechol-O-methyltransferase (COMT). This compound is used as an analytical reagent to measure levels of levodopa and its metabolites in biological samples. 2-Amino-3-(4-hydroxy-3-methoxyphenyl)propanoic acid can also be used to diagnose Parkinson’s disease, since it is produced in excess when dopamine production decreases due to the degeneration of dopaminergic neurons. The concentration–time curve for this compound can be used to calculate the clearance rate of levodopa from the blood plasma.

Chemical properties

• Molecular weight: 211.21 g/mol
• Formula: C₁₀H₁₃NO₄
• Purity: Min. 95 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C10H13NO4/c1-15-9-5-6(2-3-8(9)12)4-7(11)10(13)14/h2-3,5,7,12H,4,11H2,1H3,(H,13,14)
• InChI key: InChIKey=PFDUUKDQEHURQC-UHFFFAOYSA-N
• SMILES: COc1cc(CC(N)C(=O)O)ccc1O