4-Acetamidophenol

CAS: 103-90-2

Ref. 3D-FA15502

Product Information

• Name: 4-Acetamidophenol
• Synonyms: 4'-Hydroxyacetanilide Paracetamol, 4'-Hydroxyacetanilide, 4-(Acetylamino)phenol, 4-(N-Acetylamino)phenol, 4-Acetaminophenol, Abensanil, Acamol, Acenol, Acetagesic, Acetalgin, Acetaminofen, Acetaminophen, Algotropyl, Alpiny, Alvedon, Amadil, Aminofen, Anaflon, Anelix, Anhiba, Apamid, Apamide, Apap, Aphlogis, Banesin, Ben-u-ron, Bickie-mol, Biocetamol, Calpol, Captin, Cetadol, Claratal, Clixodyne, Crocin, Cyclopam, Dafalgan, Daga, Daphalgan, Datril, Dial-a-gesic, Dirox, Disprol, Doliprane, Dolprone, Duorol, Dymadon, Efferalgan, Endophy, Enelfa, Eneril, Eperimol, Eu-Med, Exdol, Febrilex, Febrilix, Febro-Gesic, Febrolin, Femol, Fendon, Fepanil, Finimal, Gelocatil, Hedex, Homoolan, Huangnamin, Korum, Lestemp, Liquagesic, Lonarid, Lyteca, Minoset, Momentum, Multin, N-(4-Hydroxyphenyl)acetamide, N-(4-Hydroxyphenyl)ethanamide, N-(p-Hydroxyphenyl)acetamide, N-Acetyl-4-aminophenol, N-Acetyl-4-hydroxyaniline, N-Acetyl-p-aminophenol, Napa, Napafen, Napap, Naprinol, Nebs, Nobedon, Ortensan, P-Acetylaminophenol, Pacemo, Pacemol, Pacimol, Paldesic, Pamol, Panadeine, Panadol, Panaleve, Panasorb, Panets, Panodil, Para-Tabs, Paracet, Paraceta, Paracetamol, Paracetamole, Paracip, Parageniol, Paralen, Paramol, Paraspen, Parelan, Parmol, Pedric, Perfalgan, Phenaphen, Phendon, Pinex, Prodafalgan, Puerxitong, Pyral, Pyretinol, Pyridol, Pyril, Pyrinazine, Rapidol, Resfenol, Resprin, Salzone, Sanador, Sara, Tabalgin, Tachipirina, Tapar, Temlo, Tempanal, Tempra, Tralgon, Tylenol, TylolHot, Valadol, Valgesic, Vermidon, p-(Acetylamino)phenol, p-Aceaminophenol, p-Acetamidophenol, p-Acetoaminophen, p-Hydroxyacetanilide, Acetanilide, 4′-hydroxy-, Acetamide, N-(4-hydroxyphenyl)-

Description

4-Acetamidophenol (4AP) is a natural compound that has been shown to inhibit nuclear DNA damage in vitro. It also has anti-inflammatory activity, which may be due to its ability to inhibit cyclooxygenase-1 and cyclooxygenase-2 enzymes. 4AP is synthesized by the condensation of acetaminophen with formaldehyde and sodium hydroxide. This drug binds to the signal peptide in the Toll-like receptor 2 (TLR2) protein, preventing TLR2 from activating inflammatory pathways. The matrix effect of 4AP is thought to play a role in its mechanism of action, as well as its biocompatibility with tissues.
The analytical method used for this product is high performance liquid chromatography with ultraviolet detection at 280 nm.

• Brand: Biosynth

Chemical properties

• Molecular weight: 151.16 g/mol
• Formula: C₈H₉NO₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)
• InChI key: InChIKey=RZVAJINKPMORJF-UHFFFAOYSA-N
• SMILES: CC(=O)Nc1ccc(O)cc1