Product Information
Name:2-Amino-4-methylthiophene-3-carboxamide
Synonyms:
- 2-Amino-3-carbamoyl-4-methylthiophene
Brand:Biosynth
Description:2-Amino-4-methylthiophene-3-carboxamide is a small molecule that is a potent inhibitor of the JAK2 kinase. This enzyme is associated with human fibrosis and has been shown to be involved in the development of liver fibrosis in rats. 2-Amino-4-methylthiophene-3-carboxamide inhibits the production of cytokines such as IL1α, IL6, and TNFα. It also blocks the activation of transcription factors such as NFκB, which are involved in inflammation. The compound has been shown to be orally active and has demonstrated efficacy in animal studies. Analogues have also been synthesized for this compound that show similar activity.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:156.21 g/mol
Formula:C6H8N2OS
Purity:(%) Min. 85%
Color/Form:Powder
InChI:InChI=1S/C6H8N2OS/c1-3-2-10-6(8)4(3)5(7)9/h2H,8H2,1H3,(H2,7,9)
InChI key:InChIKey=AXLIJQRGPVJGSO-UHFFFAOYSA-N
SMILES:Cc1csc(N)c1C(N)=O
Technical inquiry about: 2-Amino-4-methylthiophene-3-carboxamide
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