Atorvastatin ethyl ester

CAS: 1146977-93-6

Ref. 3D-FA165519

Product Information

• Name: Atorvastatin ethyl ester
• Brand: Biosynth
• Description: Atorvastatin ethyl ester is a prodrug of atorvastatin that is used for the treatment of hypercholesterolemia. It inhibits HMG-CoA reductase, which reduces cholesterol production in the liver. The permeation rate of atorvastatin ethyl ester is increased by coadministration with c1-c10 fatty acids, which can be achieved by taking it with food. Atorvastatin ethyl ester has been shown to have antithrombotic and anti-inflammatory effects, which are due to its inhibition of the synthesis of thromboxane A2 and prostaglandin E2. Atorvastatin also inhibits protein synthesis in some cells, such as hepatocytes and neutrophils, but not in others such as fibroblasts or platelets. This may be related to the expression of an enzyme called cytosolic phospholipase A2 (cPLA2).

Chemical properties

• Molecular weight: 586.69 g/mol
• Formula: C₃₅H₃₉FN₂O₅
• Purity: Min. 95%
• Color/Form: Powder