7-Acetamido nitrazepam

CAS: 4928-03-4

Ref. 3D-FA16920

Product Information

• Name: 7-Acetamido nitrazepam
• Synonyms: N-(2,3-Dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-7-yl)acetamide1,3-Dihydro-7-acetamido-5-phenyl-2H-1,4-benzodiazepin-2-one, 1,3-Dihydro-7-acetamido-5-phenyl-2H-1,4-benzodiazepin-2-one, 1H-1,4-Benzodiazepine, acetamide deriv., 2H-1,4-Benzodiazepin-2-one, 7-acetamido-1,3-dihydro-5-phenyl-, 7-(Acetylamino)nitrazepam, 7-Acetamido-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one, 7-Acetamidonitrazepam, 7-Acetamino-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one, 7-Acetylaminonimetazepam, N-(2,3-Dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-7-yl)acetamide, NSC 58777, Ro 05-3305, acetamide, N-(2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-7-yl)-

Description

7-Acetamido nitrazepam is a benzodiazepine derivative that is used as a hypnotic, anxiolytic and anticonvulsant. It has been shown to have a longer duration of action than diazepam, which is its parent compound. 7-Acetamido nitrazepam has been detected in the urine of geriatric patients who have taken it orally, with concentrations peaking between 1 and 2 hours after ingestion. The plasma concentration of 7-acetamido nitrazepam in Sprague Dawley rats was found to be about 3 times higher than that of triazolam, another benzodiazepine. In rat liver microsomes, 7-acetamido nitrazepam was found to be metabolized by human CYP2E1 enzymes to form N-oxides, which are then conjugated with glucuronic acid or sulphate. 7-Acetamido nitrazepam is

• Brand: Biosynth

Chemical properties

• Molecular weight: 293.32 g/mol
• Formula: C₁₇H₁₅N₃O₂
• Purity: Min. 95%
• InChI: InChI=1S/C17H15N3O2/c1-11(21)19-13-7-8-15-14(9-13)17(18-10-16(22)20-15)12-5-3-2-4-6-12/h2-9H,10H2,1H3,(H,19,21)(H,20,22)
• InChI key: InChIKey=JHTJXLGLYZQIGI-UHFFFAOYSA-N
• SMILES: CC(=O)Nc1ccc2c(c1)C(c1ccccc1)=NCC(=O)N2