4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid, sodium salt

CAS: 51023-76-8

Ref. 3D-FA16931

Product Information

• Name: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid, sodium salt
• Synonyms: Disodium 4-acetamido-4'-isothiocyanatostilbene-2,2'-disulfonateSITS
• Brand: Biosynth
• Description: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid, sodium salt (AITC-S) is a stilbene derivative with inhibitory properties. It has been shown to inhibit the uptake of camp in rat ventricular myocytes and caco-2 cells as well as the release of camp from rat renal proximal tubules. AITC-S also inhibits the transport of camp into the cells. The mechanism by which AITC-S inhibits uptake is not yet known, but it may be due to competition for a common carrier or an effect on intracellular metabolism. This compound has also been shown to have an acute ischemic protective effect on rats when administered before reperfusion following coronary artery occlusion.

Chemical properties

• Molecular weight: 498.46 g/mol
• Formula: C₁₇H₁₂N₂Na₂O₇S₃
• Purity: Min. 95%