Product Information
Name:Acetylisoniazide
Synonyms:
- 2-Acetylhydrazide-4-pyridinecarboxylic acid1-Acetyl-2-isonicotinoylhydrazideAcetyl isoniazid
Brand:Biosynth
Description:Acetylisoniazide is an antimicrobial agent that belongs to the group of enzyme inducers. It is a prodrug that is hydrolyzed by esterases in the body to picolinic acid and acetyl-CoA. Acetylisoniazide has been shown to inhibit the growth of bacteria, yeast, and fungi that are resistant to other antimicrobial agents. This drug also inhibits the production of pyrazinoic acid, a metabolite of tryptophan synthesis and an activator of macrophages. Acetylisoniazide has been shown to have a synergistic effect with isoniazid for the treatment of tuberculosis. The polymerase chain reaction (PCR) method was used for this study. Acetylisoniazide binds to human serum albumin, which decreases its solubility in water and affects its reactivity with fluorescence probes. The matrix effect was investigated using rat liver microsomes as a model system.
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Chemical properties
Molecular weight:179.18 g/mol
Formula:C8H9N3O2
Purity:Min. 95 Area-%
Color/Form:Powder
InChI:InChI=1S/C8H9N3O2/c1-6(12)10-11-8(13)7-2-4-9-5-3-7/h2-5H,1H3,(H,10,12)(H,11,13)
InChI key:InChIKey=CVBGNAKQQUWBQV-UHFFFAOYSA-N
SMILES:CC(=O)NNC(=O)c1ccncc1
Technical inquiry about: Acetylisoniazide
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