Aurintricarboxylic acid

CAS: 4431-00-9

Ref. 3D-FA171511

Product Information

• Name: Aurintricarboxylic acid
• Synonyms: 1,4-Cyclohexadiene-1-carboxylic acid, 3-[bis(3-carboxy-4-hydroxyphenyl)methylene]-6-oxo-, 3,3'-[(3-Carboxy-4-Oxocyclohexa-2,5-Dien-1-Ylidene)Methanediyl]Bis(6-Hydroxybenzoic Acid), 3,3′-[(3-Carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methylene]bis[6-hydroxybenzoic acid], 5,5-(3-Carboxy-4-Oxocyclohexa-2,5-Dienylidenemethylene)Di(Salicylic Acid), Aluminon free acid, Aurine tricarboxylic acid, Aurinetricarboxylic Acid, Benzoic acid, 3,3′-[(3-carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methylene]bis[6-hydroxy-, Benzoic acid, 5-[(3-carboxy-4-hydroxyphenyl)(3-carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-2-hydroxy-, Cac 1098, Cp 005240

Description

Aurintricarboxylic acid is a chemical that has been used as a model system to study oxidative injury. It has been shown to induce apoptosis in HL-60 cells by inhibiting the mitochondrial pathway, and can be used as an anti-inflammatory agent. Aurintricarboxylic acid has also been shown to inhibit chronic cough in mice by suppressing the release of nuclear DNA. This drug is also effective against bowel disease, which may be due to its ability to inhibit toll-like receptor and receptor activity. Aurintricarboxylic acid also inhibits dextran sulfate-induced inflammation in rats and reduces the response of lymphocytes to stimulation with mitogens or antigenic agents.

• Brand: Biosynth

Chemical properties

• Molecular weight: 422.34 g/mol
• Formula: C₂₂H₁₄O₉
• Color/Form: Powder
• InChI: InChI=1S/C22H14O9/c23-16-4-1-10(7-13(16)20(26)27)19(11-2-5-17(24)14(8-11)21(28)29)12-3-6-18(25)15(9-12)22(30)31/h1-9,23-24H,(H,26,27)(H,28,29)(H,30,31)
• InChI key: InChIKey=GIXWDMTZECRIJT-UHFFFAOYSA-N
• SMILES: O=C(O)C1=CC(=C(c2ccc(O)c(C(=O)O)c2)c2ccc(O)c(C(=O)O)c2)C=CC1=O