(2S)-2-Amino-2-[(5S)-3-chloro-4,5-dihydroisoxazol-5-Yl]acetic acid

CAS: 42228-92-2

Ref. 3D-FA17203

Product Information

• Name: (2S)-2-Amino-2-[(5S)-3-chloro-4,5-dihydroisoxazol-5-Yl]acetic acid
• Synonyms: (a-S,5S)-a-Amino-3-chloro-4,5-dihydro-5-isoxazoleacetic AcidAcivicin, (2S)-amino[(5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl]ethanoic acid, (S-(R*,R*))-4,5-Dihydro-alpha-amino-3-chloro-5-isoxazoleacetic acid, (alpha-S,5S)-alpha-Amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid, (alphaS,5S)-alpha-Amino-3-chlor-4,5-dihydro-5-isoxazolylessigsaeure, (alphaS,5S)-alpha-Amino-3-chloro-2-isoxazoline-5-acetic acid, (α-S, 5S)-α-Amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid, (αS,5S)-α-Amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid, 5-Isoxazoleacetic acid, 4,5-dihydro-alpha-amino-3-chloro-, (S-(R*,R*))-, 5-Isoxazoleacetic acid, alpha-amino-3-chloro-4,5-dihydro-, 5-Isoxazoleacetic acid, alpha-amino-3-chloro-4,5-dihydro-, (S-(R*,R*))-, 5-Isoxazoleacetic acid, α-amino-3-chloro-4,5-dihydro-, (αS,5S)-, 5-Isoxazoleacetic acid, α-amino-3-chloro-4,5-dihydro-, [S-(R*,R*)]-, Acivicin [USAN:INN], Acivicine, Acivicine [INN-French], Acivicino, Acivicino [INN-Spanish], Acivicinum, Acivicinum [INN-Latin], Amino(3-Chloro-4,5-Dihydro-1,2-Oxazol-5-Yl)Acetic Acid, Antibiotic AT 125, At 125, Brn 1074648, Nsc 163501, U 42126, Unii-O0X60K76I6

Description

(2S)-2-Amino-2-[(5S)-3-chloro-4,5-dihydroisoxazol-5-Yl]acetic acid is an inhibitor of the enzyme glutathione reductase (GR) and cytochrome P450. GR activates glutathione in cells to form a powerful antioxidant that protects against oxidative stress. (2S)-2-Amino-2-[(5S)-3-chloro-4,5-dihydroisoxazol-5-Yl]acetic acid inhibits GR and cytochrome P450 activity, leading to increased oxidative stress and neuronal death. This drug has been shown to have inhibitory properties on bowel disease by reducing the production of proinflammatory cytokines IL1β and TNFα. The compound also exhibits anti tumor response against mouse tumors by inducing apoptosis and inhibiting cell proliferation. The compound targets intracellular targets

• Brand: Biosynth

Chemical properties

• Molecular weight: 178.57 g/mol
• Formula: C₅H₇ClN₂O₃
• Purity: Min. 95%
• Color/Form: White Powder