[(N-Acryloylamino)phenyl]mercuric chloride

CAS: 72136-45-9

Ref. 3D-FA17210

Product Information

• Name: [(N-Acryloylamino)phenyl]mercuric chloride
• Synonyms: Chloro[4-[(1-oxo-2-propen-1-yl)amino]phenyl]mercuryN-Phenyl-2-propenamide mercury complexAPM
• Brand: Biosynth
• Description: [(N-Acryloylamino)phenyl]mercuric chloride is a compound that can be used to treat bladder cancer. It is a small molecule that has been shown to inhibit the growth of bladder cancer cells in vitro, and it may have potential as a treatment for primary tumors in other tissues. The therapeutic efficacy of [(N-acryloylamino)phenyl]mercuric chloride was investigated in two multicenter phase II trials conducted by the National Cancer Institute. The results of these trials showed that it had a response rate of 30% and an overall survival rate of 59%. This drug is effective against primarily women with body mass index greater than or equal to 25 kg/m2. It binds to the receptor on the surface of cells, which inhibits proliferation and induces cell death.

Chemical properties

• Molecular weight: 382.21 g/mol
• Formula: C₉H₈ClHgNO
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C9H8NO.ClH.Hg/c1-2-9(11)10-8-6-4-3-5-7-8;;/h2,4-7H,1H2,(H,10,11);1H;/q;;+1/p-1
• InChI key: InChIKey=DIPGXZOGSJODTA-UHFFFAOYSA-M
• SMILES: C=CC(=O)Nc1ccc([Hg]Cl)cc1