7-Aminoflunitrazepam

CAS: 34084-50-9

Ref. 3D-FA17364

Product Information

• Name: 7-Aminoflunitrazepam
• Synonyms: 7-Amino-5-(2-fluorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one7-Amino-1,3-dihydro-5-(2-fluorophenyl)-1-methyl-2H-1,4-be nzodiazpin-2-one, 2H-1,4-Benzodiazepin-2-one, 7-amino-5-(o-fluorophenyl)-1,3-dihydro-1-methyl-, 2H-1,4-benzodiazepin-2-one, 7-amino-5-(2-fluorophenyl)-1,3-dihydro-1-methyl-, 7-Amino-1,3-dihydro-5-(2-fluorophenyl)-1-methyl-2H-1,4-benzodiazpin-2-one, 7-Amino-5-(2-fluorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one, Ro 20-1815

Description

7-Aminoflunitrazepam is an active metabolite of flunitrazepam and a benzodiazepine. It can be detected in urine samples using an on-line LC-MS/MS method. The detection time of 7-aminoflunitrazepam is between 3 to 4 hours, which is longer than that of its parent drug, flunitrazepam. The use of monoclonal antibodies specific for fluoroquinolones allows the detection of 7-aminoflunitrazepam with high sensitivity and specificity. This method can be used to detect the presence of flunitrazepam in human serum samples, as well as in femoral vein blood samples, urine samples, and blood sputum samples. Solid phase microextraction (SPME) was used as the sample preparation technique for this study. SPME also allows for the extraction and analysis of lysine residues from protein matrices such as human serum.

• Brand: Biosynth

Chemical properties

• Molecular weight: 283.3 g/mol
• Formula: C₁₆H₁₄FN₃O
• Purity: Min. 98%
• Color/Form: Powder
• InChI: InChI=1S/C16H14FN3O/c1-20-14-7-6-10(18)8-12(14)16(19-9-15(20)21)11-4-2-3-5-13(11)17/h2-8H,9,18H2,1H3
• InChI key: InChIKey=LTCDLGUFORGHGY-UHFFFAOYSA-N
• SMILES: CN1C(=O)CN=C(c2ccccc2F)c2cc(N)ccc21