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3-Amino-2-pyrazinecarboxylic acid methyl ester
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3-Amino-2-pyrazinecarboxylic acid methyl ester

CAS: 16298-03-6

Ref. 3D-FA17474

1kg
747.00 €
50g
147.00 €
100g
156.00 €
250g
313.00 €
500g
457.00 €
Estimated delivery in United States, on Monday 17 Mar 2025

Product Information

Name:
3-Amino-2-pyrazinecarboxylic acid methyl ester
Synonyms:
  • Methyl 3-amino-2-pyrazinecarboxylate
  • 2-Amino-3-(methoxycarbonyl)pyrazine
  • 2-Pyrazinecarboxylic acid, 3-amino-, methyl ester
  • 3-Amino-2-pyrazinecarboxylic Acid Methyl Ester
  • Methyl 2-aminopyrazine-3-carboxylate
  • Methyl 3-Aminopyrazine-2-Carboxylate
  • Methyl 3-aminopyrazine-2-carboxylic ester
  • Methyl 3-aminopyrazinecarboxylate
  • NSC 123649
  • Pyrazinecarboxylic acid, 3-amino-, methyl ester
  • See more synonyms
  • Pyrazinoic acid, 3-amino-, methyl ester
Description:

3-Amino-2-pyrazinecarboxylic acid methyl ester (3APCME) is a potent anti-mycobacterial agent that inhibits the growth of Mycobacterium tuberculosis by inhibiting the synthesis of amines, which are necessary for its survival. 3APCME has also been shown to have an inhibitory effect on other bacteria that require amines for their survival, such as Escherichia coli. This agent binds to the receptor and inhibits the enzyme pyrazinase in the reaction of phenoxy with dimethylformamide. The molecular modeling studies show that 3APCME is able to bind to a hydrophobic region on the enzyme's surface and form a covalent bond through nucleophilic attack. The asymmetric synthesis results in the production of one enantiomer of 3APCME and allows for greater efficacy against mycobacteria than other agents.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
153.14 g/mol
Formula:
C6H7N3O2
Purity:
Min. 95%
Color/Form:
Powder
InChI:
InChI=1S/C6H7N3O2/c1-11-6(10)4-5(7)9-3-2-8-4/h2-3H,1H3,(H2,7,9)
InChI key:
InChIKey=INCSQLZZXBPATR-UHFFFAOYSA-N
SMILES:
COC(=O)c1nccnc1N
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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