EVP4593

CAS: 545380-34-5

Ref. 3D-FA17546

Product Information

• Name: EVP4593
• Synonyms: N4-[2-(4-Phenoxyphenyl)ethyl]-4,6-quinazolinediamineQNZ6-Amino-4-(4-phenoxyphenylethylamino)quinazoline
• Brand: Biosynth
• Description: 6-Amino-4-(4-phenoxyphenylethylamino)quinazoline is a potential anticancer drug that has been shown to inhibit the polymerase chain reaction in human osteosarcoma cells. It also inhibits the signaling pathway of nuclear factor-κB (NF-κB), which is involved in cell death and tumorigenesis. 6-Amino-4-(4-phenoxyphenylethylamino)quinazoline has shown significant cytotoxicity against murine hepatoma cells and bowel disease cells, but not against normal tissue. This drug is also an inhibitor of the drug transporter Pgp. 6-Amino-4-(4-phenoxyphenylethylamino)quinazoline has been shown to be effective in experimental models for cancer, AIDS, and other infectious diseases.

Chemical properties

• Molecular weight: 356.42 g/mol
• Formula: C₂₂H₂₀N₄O
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C22H20N4O/c23-17-8-11-21-20(14-17)22(26-15-25-21)24-13-12-16-6-9-19(10-7-16)27-18-4-2-1-3-5-18/h1-11,14-15H,12-13,23H2,(H,24,25,26)
• InChI key: InChIKey=IBAKVEUZKHOWNG-UHFFFAOYSA-N
• SMILES: Nc1ccc2ncnc(NCCc3ccc(Oc4ccccc4)cc3)c2c1