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Amphotericin A
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Amphotericin A

CAS: 1405-32-9

Ref. 3D-FA177367

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Estimated delivery in United States, on Wednesday 18 Dec 2024

Product Information

Name:
Amphotericin A
Synonyms:
  • 14,39-Dioxabicyclo[33.3.1]nonatriacontane, amphotericin B deriv.
  • 28,29-Dihydroamphotericin B
  • 33-[(3-Amino-3,6-Dideoxyhexopyranosyl)Oxy]-1,3,5,6,9,11,17,37-Octahydroxy-15,16,18-Trimethyl-13-Oxo-14,39-Dioxabicyclo[33.3.1]Nonatriaconta-19,21,25,27,29,31-Hexaene-36-Carboxylic Acid
  • Amphotericin B, 28,29-dihydro-
Description:

Amphotericin A is a polyene antifungal drug that binds to ergosterol in the fungal cell membrane and disrupts membrane permeability. It is used clinically to treat systemic fungal infections, including cryptococcal meningitis, cryptococcal pneumonia, and candidiasis. Amphotericin A has been shown to inhibit growth factor-mediated protein synthesis in mammalian cells. Amphotericin A has been shown to be effective against a mutant strain of Coccidioides immitis that is resistant to rifampin, but not against other strains of this fungus. It also inhibits the methylation of DNA by a nitrogen atom transferase enzyme in Cryptococcus neoformans.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
926.09 g/mol
Formula:
C47H75NO17
Purity:
Min. 95%
MDL:
Melting point:
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Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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